📣 Second Pre-Clinical Study on Symetrian™ Published

Leading the Pack in Pet Oral Wellness

Periodontal disease is the most prevalent disease in companion carnivores with a prevalence estimate between 44% and 64%.1,2 However, most treatment options do not address the potentially damaging and often painful inflammation that is caused by the overly aggressive immune response to oral bacteria.

Oravestin™ is a proprietary blend of two plan extracts clinically proven to help control oral inflammation and bacterial growth.  The major active compounds in Oravestin™ have been shown to significantly reduce gum inflammation and plaque causing bacteria.

What Makes Oravestin™ Unique?*

  • Oravestin™ is a potent Cyclooxygenase and Lipoxygenase Dual Inhibitor to help control the inflammation in all 4 stages of periodontitis
  • Clinically proven to aid in controlling oral inflammation and bacterial growth
  • Significantly reduces gum inflammation and plaque causing bacteria
  • Natural, standardized composition from herbs known for historically safe usage
  • Proprietary ingredient, patent pending

Key Benefits*

  • Clinically proven to reduce both oral inflammation and bacteria
  • Effective dual COX/LOX inhibitor to help control inflammation in all 4 stages of periodontitis
  • Potent antimicrobial against oral bacteria
  • Significantly reduces plaque and gingivitis indexes
  • Extensive in vitro and in vivo safety testing with no adverse effects
  • High compatibility in formulating with other ingredients
  • Proprietary ingredient, patent pending

Origin (Botanical)

Derived from the roots of Scutellaria baicalensis and heartwoods of Acacia catechu.


Helps control oral inflammation and bacterial infection.


Can be used as an active agent in a range of oral products, including toothpaste, chews, tablets, capsules, liquids, powders and other delivery systems.

Physical Properties

Greenish yellow to brown colored powder that partially dissolves in water.

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* Indications, claims and usage related to the benefits or property of the ingredient or product are governed in accordance with country-specific laws and regulations. Information is provided for scientific and educational purposes related to this ingredient only. 1Kortegaard HE, Eriksen T, Baelum V. Periodontal disease in research beagle dogs–an epidemiological study. J Small Anim Pract. 2008 Dec;49(12):610-6. doi: 10.1111/j.1748-5827.2008.00609.x. Epub 2008 Sep 12. PMID: 18793256. 2Niemiec BA. Periodontal disease. Top Companion Anim Med. 2008 May;23(2):72-80. doi: 10.1053/j.tcam.2008.02.003. PMID: 18482707.