Unigen Announces Approval of 99% Bakuchiol as a New Skincare Cosmetic Ingredient by China’s NMPA
TACOMA, WASHINGTON – September 15, 2025: Unigen Inc., a natural product R&D and proprietary ingredient supplier, has received approval from China’s Natural Medical Products Administration (NMPA) for its patented 99% Bakuchiol as a skin protectant, moisturizer, and antioxidant (INCI name: Bakuchiol; Registration Certificate No.20250112). The approved skin care applications include Body Care & Cleansing: Sunscreen, body lotion, hand cream, shower gel; Facial Skincare & Makeup: Face cream, serum, mask, toner, eye cream, cleansing foam, and more. Unigen’s 99% Bakuchiol is approved for cosmetic formulations with a maximum usage level of 3%.
Unigen’s Chief Scientific Officer, Dr. Qi Jia emphasized that NMPA’s approval holds profound industry significance and marks a momentous achievement in advancing natural, plant-derived active ingredients for safer and more effective skincare solutions. “The successful registration of 99% Bakuchiol in China will open the door for global brands to use Unigen’s brand-named and patented Bakuchiol in the China market. This approval is the result of a strong collaboration between Unigen and its strategic partner – Honsea Sunshine BioTech – in China.”
Unigen’s President & Chief Executive Officer, Regan Miles, stated: “NMPA’s approval has demonstrated the commitment of Unigen to scientific integrity and clinical evidence for the beauty ingredient 99% Bakuchiol. With China NMPA’s approval and Unigen’s strong relationship with global leading brands, this further expands Unigen’s ability to bring our innovative products to an international market and discerning consumer.“
Unigen’s 99% Bakuchiol is extracted with supercritical fluid and purified by molecular distillation after hydrolysis to remove prototoxins. This production technology is the foundation for consistent, high quality and competitive Bakuchiol approved by NMPA, explained Dr. Jia. Unigen has carried out 4 clinical trials of Bakuchiol composition for acne, acne spot, post inflammatory hyperpigmentation and photoaging, with peer-reviewed publications and issued global patents.
Unigen has developed two applications for 99% Bakuchiol (UP256-3) under two trade names – Bakutrol® A and Lumicyn™ Pure. Bakutrol® A is a natural alternative to Benzoyl Peroxide with potent anti-microbial, anti-inflammatory and anti-oxidation activities. Two clinical trials of Bakutrol demonstrated visible improvement of the appearance of acne blemishes, especially those due to inflammatory acne. Lumicyn’s in vitro study showed unique modulations of multiple pigmentation production and delivery pathways with clinically proven and statistically significant reduction of post inflammatory hyperpigmentation in two peer-reviewed publications of clinical trials. A recent anti-photoaging study in the US also demonstrated that Unigen’s Lumicyn improved skin health and appearance with reduced brown spots, pore size, porphyrins, and wrinkles.
For further information about Bakutrol® A, Lumicyn™ Pure and the Unigen Beauty portfolio, please contact:
SALES INQUIRIES
Rodney E. Storms, JD
Executive Sales Director
Email: rstorms@unigen.net
Website: unigen.net/unigenbeauty
MEDIA INQUIRIES
Kathy Markham
Marketing Manager,
Unigen, Inc.
Email: kmarkham@unigen.net
Website: unigen.net
About Unigen, Inc.
Unigen discovers, develops, and manufactures proprietary natural-product active ingredients for dietary supplements, cosmetic and personal care products, prescription medical food and botanical drug products. The Company discovers its ingredients through its high-throughput screening PhytoLogix® approach applied to a proprietary well-annotated collection of botanicals and a legacy mining approach applied to botanicals having known medicinal benefits.
Mechanism of action, safety, and efficacy are documented with extensive preclinical in vitro and by human clinical studies. Unigen protects its discoveries with issued patents and patent filings in all major territories and manufactures its products to GMP standards. Unigen commercializes its proprietary ingredients through licensing and ingredient supply alliances with commercial partners engaged in the manufacture, distribution, and marketing of end-products in each of Unigen’s target markets.